Vaccine Info

VXA‑G1.1-NN Norovirus

VXA-G1.1-NN is an Oral Vaccine Candidate Tablet addressing Norovirus.

Norovirus is a pathogen that infects the small intestine, Vaxart believes a vaccine that produces mucosal antibodies locally in the intestine, in addition to systemic antibodies that circulate in the blood, may better protect against norovirus infection than an injectable vaccine.

May 30, 2018, Vaxart has completed two Phase 1 clinical trials with its monovalent oral tablet vaccine based on the GI.1 norovirus strain.

The norovirus tablet vaccine was well tolerated and generated broad systemic and mucosal immune responses.

In the first half of 2019, Vaxart plans to initiate a Phase 1 trial of its bivalent norovirus vaccine candidate designed to assess safety and immunogenicity and commence a Phase 2 challenge study with its GI.1 monovalent vaccine designed to assess the protective efficacy against live norovirus challenge.


April 30th, 2019